

History of SAMe
1970s,SAMe is approved in Europe as a prescription drug for treating arthritis;
1980s,SAMe is recommended as an anti-depressant in Europe;
1996,The US FDA has officially approved SAMe's intestinal soluble form as an OTC drug.
1999,The FDA has approved SAMe for sale as a food nutritional supplement

What is SAMe?
S-adenosylmethionine(SAMe) is a physiologically active substance that exists in all tissues and body fluids of the human body. It serves as a methyl donor (transmethylation) and a precursor (transsulfuration) for biochemical compounds with a sulfur group (such as cysteine, taurine, glutathione, and coenzyme A) and participates in over 40 important biochemical reactions in the body. It is closely linked to the biosynthesis of proteins, nucleic acids, neurotransmitters, phospholipids, and vitamins.


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